Retatrutide Weight Loss in Phoenix

Physician supervised retatrutide programs for adults wanting the most advanced GLP 1 class option available. Hospital grade medication, triple receptor action, and personalized monitoring.

What Is Retatrutide?

Retatrutide is a triple agonist medication that activates GLP 1, GIP, and glucagon receptor pathways at the same time. It is currently in late stage clinical trials and is the newest medication in the GLP 1 class. Early clinical results have shown the highest weight loss percentages of any medication in this class.


Retatrutide builds on the dual action of tirzepatide by adding glucagon receptor activity. Glucagon is a hormone that affects how the body uses energy and metabolizes fat. The triple agonist action may produce more comprehensive metabolic effects than any current GLP 1 medication.


At The Good Life IV, retatrutide is provided as a prescription medication under physician supervision. Because retatrutide is newer and still in clinical trials, it is available only through licensed compounding pharmacies. Our Medical Director reviews your health history carefully before recommending retatrutide.

How Retatrutide Works

Retatrutide works on three hormone pathways. The GLP 1 effects reduce hunger and slow stomach emptying. The GIP effects support metabolic response. The glucagon effects influence energy expenditure and fat metabolism. Together these three pathways produce comprehensive effects on appetite, metabolism, and body composition.



Clinical trials have shown retatrutide produces the highest average weight loss of any medication in the GLP 1 class. Some trial participants have lost 24 percent or more of their body weight over the study period. The medication is still being studied for full safety and efficacy data.


Retatrutide is given as a weekly subcutaneous injection. Dosing starts low and titrates up gradually. Because retatrutide is newer, our Medical Director uses careful protocols informed by current clinical research and pharmacy best practices.

Key Benefits of Retatrutide

  • Highest Average Weight Loss in the Class

    Clinical trial results have shown retatrutide producing average weight loss of 22 to 24 percent of body weight, the highest of any GLP 1 class medication.

  • Triple Receptor Action

    By activating GLP 1, GIP, and glucagon receptors, retatrutide provides more comprehensive metabolic effects than single or dual agonist medications.

  • Strong Appetite Suppression

    Most retatrutide users report dramatic reductions in hunger and food cravings, often stronger than with semaglutide or tirzepatide.

  • Glucagon Activity Supports Fat Metabolism

    The added glucagon receptor activity may influence how the body uses fat for energy, potentially supporting body composition changes.

  • Weekly Dosing

    Retatrutide is taken once per week, similar to other GLP 1 medications.

  • Cutting Edge Option

    Retatrutide represents the latest advancement in GLP 1 class medications, available for adults wanting the most current option.

Who Is Retatrutide For?

Retatrutide is most commonly used by adults wanting the strongest current GLP 1 class option available. It may be a good fit if you fall into any of these categories.


  • Adults with a BMI of 27 or higher
  • People wanting the highest average weight loss available
  • Adults who have tried semaglutide or tirzepatide without enough results
  • People interested in cutting edge weight loss medication
  • Adults with significant weight loss goals
  • People comfortable with newer medications still in clinical trials

Who Should Not Use Retatrutide

Retatrutide is not appropriate for everyone. People in these categories should not use retatrutide.


  • People with a personal or family history of medullary thyroid carcinoma
  • People with multiple endocrine neoplasia syndrome type 2
  • Pregnant or nursing women
  • People with severe gastrointestinal disease
  • Anyone with active eating disorders without specialist clearance
  • Children and adolescents under 18
  • People uncomfortable using medications still in clinical trials


Our Medical Director reviews your full health history during your consultation.

How Our Program Works

Every medical weight loss protocol starts with a consultation and Good Faith Exam with our Medical Director, Dr. Decker Weiss, NMD, FASA. We use medications from licensed compounding pharmacies that meet United States Pharmacopeia standards. Baseline lab work is typically required. Dosing starts low and titrates up. Follow ups are scheduled regularly to monitor progress and adjust as needed.

What to Expect

Timeline

Most retatrutide users notice reduced hunger within the first 1 to 2 weeks. Weight loss typically begins by week 2 to 4 and continues at a steady pace. Clinical trials have shown significant weight loss continuing through 48 to 72 weeks of treatment.


Common Experiences

Retatrutide users often report the strongest appetite suppression of any GLP 1 medication. Food noise reductions can be dramatic. Some users describe feeling like food no longer has the same pull it used to. Side effects during titration are similar to other GLP 1 medications but may be more pronounced for some users.


Side Effects

Common retatrutide side effects include nausea, constipation, diarrhea, fatigue, and occasional vomiting, especially during dose increases. The full long term side effect profile is still being studied because retatrutide is newer than semaglutide and tirzepatide. Our Medical Director provides full disclosure and monitors you carefully throughout treatment.

Retatrutide Pricing

Compounded retatrutide typically costs $500 to $700 per month including the medication and physician monitoring. Pricing may change as retatrutide moves through clinical trials and toward potential FDA approval.

Frequently Asked Questions About Retatrutide

  • Is retatrutide approved by the FDA?

    Retatrutide is currently in late stage clinical trials and is not yet FDA approved for weight loss. It is available through licensed compounding pharmacies under physician prescription.

  • How is retatrutide different from semaglutide and tirzepatide?

    Semaglutide activates one receptor (GLP 1). Tirzepatide activates two (GLP 1 and GIP). Retatrutide activates three (GLP 1, GIP, and glucagon). The triple action may produce more comprehensive effects.

  • How much weight will I lose on retatrutide?

    Clinical trials have shown average weight loss of 22 to 24 percent of body weight. Individual results vary based on dose, lifestyle, and starting weight.

  • Is retatrutide safe?

    Retatrutide has shown a similar safety profile to other GLP 1 medications in clinical trials, though longer term data is still being collected. Use under physician supervision is essential.

  • Can I switch from tirzepatide to retatrutide?

    Yes. Some adults switch from tirzepatide to retatrutide if they want stronger results. Your Medical Director will guide you through any transition.

  • Will insurance cover retatrutide?

    Because retatrutide is not yet FDA approved, insurance does not currently cover it. Some HSA and FSA accounts may apply.

  • Why is retatrutide more expensive than other options?

    Retatrutide is newer and currently available only through specialized compounding pharmacies. As the medication moves through clinical trials, pricing may evolve.

  • What happens if I stop retatrutide?

    Like other GLP 1 medications, most people regain some or all of the weight they lost if they stop retatrutide without significant lifestyle changes.

Start Retatrutide in Phoenix

Retatrutide may be a useful tool in your weight loss journey. Book a consultation with our Medical Director to find out if it is right for you.